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NCT04452162 | RECRUITING | Salivary Gland Tumor

Physiologic MR Imaging of Salivary Gland Tumors
Sponsor:

Abramson Cancer Center at Penn Medicine

Information provided by (Responsible Party):

Sanjeev Chawla

Brief Summary:

The goal of this study is to use advanced Magnetic Resonance Imaging (MRI) techniques to help identify the difference between cancerous and non-cancerous salivary gland tumors for improving treatment strategies and to aid in the prediction of disease progression.

Condition or disease

Salivary Gland Tumor

Intervention/treatment

MRI

Phase

NA

Detailed Description:

The goal of this proposed study is to investigate the potential utility of combined analysis of parameters (Ktrans, ti and ADC) in discriminating benign from malignant salivary glands tumors (SGTs). A total of 30 treatment naïve patients suspicious of SGT as observed on clinical evaluation and prior routine CT, MRI, Ultrasound, FNAC and/or PET will undergo 3T MRI. The MRI protocol will include acquisition of anatomical images with and without contrast agent injection, diffusion imaging and dynamic contrast enhanced-MRI.

Study Type : INTERVENTIONAL
Estimated Enrollment : 30 participants
Masking : NONE
Primary Purpose : DIAGNOSTIC
Official Title : Physiologic MR Imaging in Distinguishing Benign From Malignant Salivary Gland Tumors
Actual Study Start Date : 2020-08-25
Estimated Primary Completion Date : 2025-06
Estimated Study Completion Date : 2025-06

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Possess a salivary gland lesion of 1cm3 size
  • * Have no prior history of treatment for salivary gland lesion
Exclusion Criteria
  • * Has any prior history of cancer other than SGT
  • * Has any MRI contra-indications
  • * Has a history of known renal disease.
  • * Has history of prior radiation to head and neck region
  • * Is pregnant
Physiologic MR Imaging of Salivary Gland Tumors

Location Details

NCT04452162

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How to Participate

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Locations

RECRUITING

United States, Pennsylvania

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104