University Hospital, Akershus
Christopher Inchley
Prospective cohort study of COVID-19 infection among children in Norway.
Pediatric Respiratory Diseases
COVID
Fatigue Post Viral
This nation-wide, prospective cohort study of COVID-19 infection addresses three main issues: 1) Epidemiological risk factors; 2) Natural history (including immunological mechanisms and long term effects) and 3) Support of infection prevention. Also, the study focuses solely on children. Children (0-18 years of age) admitted to hospital with suspected COVID-19 are eligible (Fig. 1). Those with confirmed COVID-19 serve as cases, whereas those with non-COVID-19 serve as controls; both groups will be followed prospectively for 6 months. Three objectives/Work Packages (WPs) are defined: * In WP1, the investigators will investigate risk factors for severe outcome of the acute infection; potential risk factors include sex, age, comorbidities, initial clinical findings, infectious load, and genetic markers. * In WP2, the investigators will investigate the immunological response to acute infection, focusing on initial innate host response and its associations to inflammatory enhancement, genetic factors and clinical course. * In WP3, the investigators will investigate the prevalence and risk factors of long-lasting complication, in particular the development of post-infectious chronic fatigue
| Study Type : | OBSERVATIONAL |
| Estimated Enrollment : | 350 participants |
| Official Title : | COVID-19 in Hospitalised Norwegian Children - Risk Factors, Outcomes and Immunology |
| Actual Study Start Date : | 2020-04-03 |
| Estimated Primary Completion Date : | 2030-12-31 |
| Estimated Study Completion Date : | 2030-12-31 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | to 18 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
Akershus University Hospital
Lørenskog, Norway,