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NCT04074538 | RECRUITING | Colorectal Cancer

the National Colorectal Cancer Cohort (NCRCC) Study: National Colorectal Cancer Research Consortium
Sponsor:

ding KE-Fe ng

Information provided by (Responsible Party):

ding KE-Fe ng

Brief Summary:

NCRCC study is a national prospective cohort study including colorectal cancer screening population and stage Ⅰ-Ⅳ colorectal cancer patients.

Condition or disease

Colorectal Cancer

Detailed Description:

NCRCC study is a large-scale multicenter study which includes 16 hospitals and research centers, establishing a national cohort which consists of two subcohorts (CRC Screening Cohort and Colorectal Cancer Patient Cohort). 1. To assess risk factors for colorectal cancer and evaluate risk prediction model of colorectal cancer to identify the high-risk population. 2. To discover, test and validate new biological markers (e.g. genetic, epigenetic, transcriptomic, metabolomics, proteomic and metagenomics biomarkers) for early diagnosis, prediction of clinical outcomes (e.g. therapeutic response, toxicity, surgical complications) and survivorship endpoints (e.g. recurrence, survival, quality of life, second primary cancer). 3. To estimate associations of epidemiological determinants (e.g. medication and supplement use, diet, lifestyle pattern) with clinical outcomes and survivorship endpoints among CRC patients.

Study Type : OBSERVATIONAL
Estimated Enrollment : 55000 participants
Official Title : The National Colorectal Cancer Cohort Study-Precision Medical Research in Colorectal Cancer
Actual Study Start Date : 2013-01-01
Estimated Primary Completion Date : 2035-12
Estimated Study Completion Date : 2035-12

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Men and women
  • * Mentally/physically able to consent and participate
  • * Subjects aged ≥18 years old (Colorectal Cancer Patient Cohort, CRCPC), age 40-74 years (CRC Screening Cohort, CRCSC)
  • * Newly-diagnosed colon and rectal cancer for stages Ⅰ-Ⅳ (CRCPC)
Exclusion Criteria
  • * A history of colorectal cancer or bowel resection
  • * Non-Chinese speaking
the National Colorectal Cancer Cohort (NCRCC) Study: National Colorectal Cancer Research Consortium

Location Details

NCT04074538

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

China, Zhejiang

Second Affiliated Hospital Zhejiang University College of Medicine

Hangzhou, Zhejiang, China, 310999

RECRUITING

China,

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Beijing, China,

RECRUITING

China,

West China Hospital

Chengdu, China,

RECRUITING

China,

Sun Yat-sen University

Guangzhou, China,

RECRUITING

China,

Shanghai Z Sequoia Hospital

Shanghai, China,