University of Florida
This mechanistic clinical trial proposes to test whether a five-day course of mindfulness meditation training (MMT) and tDCS, and their combination, can enhance pain modulatory balance and pain-related brain function, reduce clinical pain, among African Americans and non-Hispanic whites with knee osteoarthritis (OA). This approach will provide evidence that targeting stress and pain-related brain function will reduce OA-related pain and ethnic group differences therein.
Osteoarthritis of Knee
Focused Breathing and Attention Training (BAT)
Standard Breathing and Attention Training (BAT)
Transcranial Direct Current Stimulation (tDCS)
Sham Transcranial Direct Current Stimulation (tDCS)
NA
Study Type : | INTERVENTIONAL |
Estimated Enrollment : | 240 participants |
Masking : | DOUBLE |
Masking Description : | Participants will be block randomized with stratification for site, sex, and race in double blind fashion. |
Primary Purpose : | TREATMENT |
Official Title : | Pain Relief for OsteoArthritis Through Combined Treatment (PROACT) |
Actual Study Start Date : | 2020-03-13 |
Estimated Primary Completion Date : | 2025-02-28 |
Estimated Study Completion Date : | 2025-02-28 |
Information not available for Arms and Intervention/treatment
Ages Eligible for Study: | 45 Years to 85 Years |
Sexes Eligible for Study: | ALL |
Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
University of Alabama at Birmingham
Birmingham, Albama, United States, 35294
RECRUITING
University of Florida
Gainesville, Florida, United States, 32610