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NCT03744065 | COMPLETED | Hip Osteoarthritis

Lumbar Plexus and Suprainguinal Fascia Iliaca Blocks For Total Hip Replacement
Sponsor:

University of Chile

Information provided by (Responsible Party):

Daniela Bravo Advis

Brief Summary:

The nerves from lumbar plexus (LP) are the current target to achieve analgesia after a total hip arthroplasty (THA). Lumbar plexus block (LPB) is an alternative that provides optimal postoperative analgesia. However, many adverse effects and complications have been reported due to its proximity to vital structures. Because of these shortcomings, an alternative to block the LP nerves is required. In a recent trial suprainguinal Fascia Iliaca Block (SFIB) was reported to provide reliable analgesia in THA. SFIB may carry a lower risk profile, however, no study has compared the efficacy of LPB and SFIB in this setting. Thus, this randomized trial is set out to compare US guided LPB and SFIB for analgesia after THA. The hypothesis is that both blocks would result in similar postoperative opioid (morphine) consumption at 24 hours and, therefore, designed the study as an equivalence trial.

Condition or disease

Hip Osteoarthritis

Pain, Acute

Pain, Postoperative

Opioid Use

Intervention/treatment

lumbar plexus block

suprainguinal fascia iliaca block

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 60 participants
Masking : DOUBLE
Primary Purpose : TREATMENT
Official Title : A Randomized Comparison Between Ultrasound Guided Lumbar Plexus and Suprainguinal Fascia Iliaca Blocks For Total Hip Replacement Analgesia
Actual Study Start Date : 2018-11-19
Estimated Primary Completion Date : 2020-01-22
Estimated Study Completion Date : 2020-01-23

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 80 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Age between 18 and 80 years
  • * American Society of Anesthesiologists classification 1-3
  • * Body mass index between 20 and 35 (kg/m2)
Exclusion Criteria
  • * Adults who are unable to give their own consent
  • * Pre-existing neuropathy (assessed by history and physical examination)
  • * Coagulopathy (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. platelets ≤ 100, International Normalized Ratio ≥ 1.4 or prothrombin time ≥ 50)
  • * Renal failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. creatinine ≥ 100)
  • * Hepatic failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. transaminases ≥ 100)
  • * Allergy to local anesthetics (LAs) or morphine
  • * Pregnancy
  • * Prior surgery in the corresponding side of the lumbar o suprainguinal area
  • * Chronic pain syndromes requiring opioid intake at home
Lumbar Plexus and Suprainguinal Fascia Iliaca Blocks For Total Hip Replacement

Location Details

NCT03744065

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How to Participate

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Locations

Not yet recruiting

Chile, Metropolitan

University of Chile Clinical Hospital

Santiago, Metropolitan, Chile, 8380456