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NCT03196310 | RECRUITING | Osteoarthritis Thumb

Single Blinded First CMC Osteoarthritis Treatment
Sponsor:

Kettering Health Network

Brief Summary:

Single blinded PRP vs. Corticosteroid vs. Placebo (normal saline) intra-articular injection for basal joint arthritis.

Condition or disease

Osteoarthritis Thumb

Intervention/treatment

Platelet Concentrate

Corticosteroid injection

Normal Saline

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 150 participants
Masking : SINGLE
Masking Description : Patients will be blinded to therapy they receive
Primary Purpose : TREATMENT
Official Title : Randomized Single Blinded First CMC Osteoarthritis Treatment: Therapy and Bracing Alone vs. Intra-Articular Corticosteroid Injection vs Intra-Articular Leukocyte Depleted Platelet Rich Plasma
Actual Study Start Date : 2018-09-01
Estimated Primary Completion Date : 2025-03-31
Estimated Study Completion Date : 2025-03-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Stage 1-3 osteoarthritis of the basal joint
Exclusion Criteria
  • * Patients with Stage 4 1st carpometacarpal joint arthritis as described by Eaton
  • * Patients who have received a corticosteroid injection in the last year to the 1st CMC joint on the proposed study side
  • * Patients who have scaphotriquetral, radioscaphoid, or scaphotrapezial osteoarthritis
  • * Patients who have concurrent DeQuervain's tenosynovitis or intersection syndrome or have been treated for either of these in the last 3 months
  • * Patients undergoing evaluation of cervical radiculopathy
  • * Patients with fibromyalgia or inflammatory rheumatic disease
  • * Patients with Pressier disease, Kienbock's, or avascular necrosis of the scaphoid
  • * Patients with any history of primary or secondary bone tumor
  • * Patients that are pregnant or terminally ill
Single Blinded First CMC Osteoarthritis Treatment

Location Details

NCT03196310

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Ohio

Orthopedic Associates of Southwest Ohio

Centerville, Ohio, United States, 45459