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NCT02024542 | RECRUITING | Morbid Obesity


Metabolic Responses to Bariatric Surgery
Sponsor:

University of California, Davis

Brief Summary:

Research the genetic and biomechanical markers of human adipose tissue on patients with morbid obesity. Additional tissue/fluid collection is also gathered during the time of surgery.

Condition or disease

Morbid Obesity

Intervention/treatment

Surgery

Detailed Description:

Study participation by invitation after complete pre-surgical work up at UC Davis Health System. Patients will be invited to participate if they meet all inclusion criteria's after completing all necessary clinical visits including lab studies, counseling, and participation in educational programs. During the pre-operative visit patients interested in participation will complete all necessary consent documentation. Pre-operative labs (blood and urine) will be collected along with additional blood, urine, and fecal samples will be collected pre-operatively. During surgery (Roux-en-Y Gastric Bypass surgeries only) tissue collection will include subcutaneous \& omental fat, jejunum, and liver biopsy. Post surgery patient will be observed for weight loss and resolution of co-morbidities. At designated times post surgery when lab studies are ordered additional blood/urine samples will be collected and analyzed.

Study Type : OBSERVATIONAL
Estimated Enrollment : 500 participants
Official Title : Genetic and Biochemical Characteristics of Medically-Complicated Obesity and Response to Bariatric Surgery
Actual Study Start Date : 2011-02
Estimated Primary Completion Date : 2035-04
Estimated Study Completion Date : 2035-04

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 55 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Meet NIH Criteria for Bariatric Surgery
  • * Between the Age of 18-55
  • * Dyslipidemia controlled with medication
  • * Impaired glucose metabolism or type 2 diabetes
Exclusion Criteria
  • * Uncontrolled Metabolic syndrome (uncontrolled diabetes, htn, dyslipidemia), one or all conditions.

Metabolic Responses to Bariatric Surgery

Location Details

NCT02024542


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Locations


RECRUITING

United States, California

University of California Davis Medical Center

Sacramento, California, United States, 95817

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