University of Arizona
The main objective of this research project is to provide a comprehensive clinical database of patients with Alzheimer's disease (AD) and other forms of dementia, individuals with mild cognitive impairment (MCI), and age-matched normal controls. The study will also attempt to identify cognitively normal individuals at genetically defined risk for Alzheimer's disease through genetic screening. All participants are seen annually. Autopsies to establish diagnoses in patients with dementia, patients with mild MCI, and cognitively normal elderly control subjects will also be conducted.
Alzheimer's Disease
Mild Cognitive Impairment
Age-Related Memory Disorders
All participants are seen annually. In addition to a detailed neurological examination, participants will receive a standardized battery of neuropsychological tests and will undergo genetic testing. The investigators will provide standardized periodic longitudinal assessment of the research participants. Autopsies to establish neurohistopathological diagnoses in clinically well-characterized patients with dementia, patients with mild MCI, and cognitively normal elderly control subjects will also be conducted.
| Study Type : | OBSERVATIONAL |
| Estimated Enrollment : | 900 participants |
| Official Title : | Arizona Alzheimer's Disease Core Center |
| Actual Study Start Date : | 2001-07 |
| Estimated Primary Completion Date : | 2024-12 |
| Estimated Study Completion Date : | 2025-07 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 50 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: | 1 |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
University of Arizona, University Medical Center
Tucson, Arizona, United States, 85724