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NCT01207167 | RECRUITING | Atherosclerosis

Mediators of Atherosclerosis in South Asians Living in America
Sponsor:

University of California, San Francisco

Brief Summary:

South Asian (Indian, Pakistani, Bangladeshi, Nepali, and Sri Lankan) individuals have high rates of cardiovascular disease that is not explained by traditional cardiovascular risk factors. Though South Asians represent over one-quarter of the world's population, there are no longitudinal studies in this high-risk ethnic group. The investigators aim to establish a longitudinal study of South Asians at three United States centers to identify risk factors linked to subclinical atherosclerosis and incident cardiovascular disease. The purpose of this study is to understand the causes of heart disease and stroke in South Asians and compare these causes to those in other United States ethnic groups.

Condition or disease

Atherosclerosis

Cardiovascular Diseases

Heart Diseases

Coronary Artery Disease

Coronary Disease

Study Type : OBSERVATIONAL
Estimated Enrollment : 2314 participants
Official Title : Mediators of Atherosclerosis in South Asians Living in America
Actual Study Start Date : 2010-09
Estimated Primary Completion Date : 2013-03
Estimated Study Completion Date : 2025-12

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 40 Years to 84 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * South Asian ancestry defined by having at least 3 grandparents born in one of the following countries: India, Pakistan, Bangladesh, Nepal, or Sri Lanka
  • * age between 40 and 84 years.
Exclusion Criteria
  • * Physician diagnosed heart attack, stroke or transient ischemic attack (TIA), heart failure, or angina (or use of nitroglycerin)
  • * Current atrial fibrillation
  • * Past history of cardiovascular procedures (coronary artery bypass graft (CABG) Surgery, angioplasty, valve replacement, pacemaker or defibrillator implantation, or any surgery on the heart or arteries)
  • * Active treatment for cancer
  • * Life expectancy less than 5 years due to serious medical illness
  • * Impaired cognitive ability as judged by the reviewer
  • * Plans to move out of the study region in next 5 years
  • * Weight greater than 300 pounds
  • * Living in a nursing home or on a waiting list
  • * Unable to speak/read/write English, Hindi, Urdu, or Bangla
Mediators of Atherosclerosis in South Asians Living in America

Location Details

NCT01207167

Please Choose a site

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

ACTIVE NOT RECRUITING

United States, California

University of California, San Francisco

San Francisco, California, United States, 94115

RECRUITING

United States, Illinois

Northwestern University

Chicago, Illinois, United States, 60611

RECRUITING

United States, New York

New York University

New York, New York, United States,