Thinking of joining a study?

Register your interest

Become a volunteer?

NCT01042548 | RECRUITING | Breast Cancer

Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
Sponsor:

University of Pittsburgh

Information provided by (Responsible Party):

Min sun

Brief Summary:

The current study is a case control study involving comparisons of tissue interstitial fluid from breast cancer and adjacent non-cancerous tissue as well as that from benign breast lesion and its adjacent non-diseased tissue for a distinguishable breast cancer profile. The purpose of this research is to collect fresh breast nodule/cancer and surrounding non-cancerous tissue for proteomic studies of the interstitial fluid to identify a profile distinguishing breast cancer which will also permit future research on stored interstitial fluid, blood or tissue samples. Specific markers identified from interstitial fluid study will be investigated in blood samples to develop serum markers for breast cancer diagnosis and prognosis. Additionally, we will perform both prospective and retrospective research on breast cancer involving clinical, demographic, epidemiologic information, treatment, follow-up and outcomes on breast nodule/cancer cases collected.

Condition or disease

Breast Cancer

Study Type : OBSERVATIONAL
Estimated Enrollment : 300 participants
Official Title : Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
Actual Study Start Date : 2010-02-03
Estimated Primary Completion Date : 2028-04
Estimated Study Completion Date : 2028-04

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * All subjects ≥ 18 years of age undergoing surgery for indeterminate breast nodules, breast tissue reduction, prophylactic mastectomy, and all subjects with newly diagnosed invasive breast cancer will be eligible to participate. If invasive breast cancer or suspicion of invasive breast cancer, target lesion must measure ≥ 1.0 cm on breast imaging before core biopsy.
Exclusion Criteria
  • * Anyone \< 18 years of age.
  • * Multiple synchronous primary malignancies from different organ systems.
Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum

Location Details

NCT01042548

Please Choose a site

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Pennsylvania

UPMC St. Margaret

Pittsburgh, Pennsylvania, United States, 15215