University of Michigan
X UE set Wang
The purpose of this feasibility study is to determine if a new emerging technology called photoacoustic tomography (PAT) can be adapted for use in humans for the detection of chronic rheumatoid arthritis.
Arthritis, Rheumatoid
Laser Based Photoacoustic Tomography, MRI, Ultrasound
laser based photoacoustic tomography, MRI, ultrasound
The objective of this proposal is to adapt photoacoustic tomography (PAT), a novel, nonionizing, noninvasive, laser-based technology, for structural and functional imaging of human peripheral joints affected by inflammatory arthritis. Combining the advantages of both light and ultrasound scanning, PAT holds promise to present objective optical information in subsurface joint tissues with high sensitivity and high spatial resolution. This could be of considerable help in the early detection of inflammatory joint diseases. PAT may also prove useful in further understanding the pathophysiology of these disorders and assisting with therapeutic decisions, including assessment of new pharmacological therapies.
Study Type : | OBSERVATIONAL |
Estimated Enrollment : | 177 participants |
Official Title : | Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis |
Actual Study Start Date : | 2011-12-01 |
Estimated Primary Completion Date : | 2025-06 |
Estimated Study Completion Date : | 2025-06 |
Information not available for Arms and Intervention/treatment
Ages Eligible for Study: | 18 Years |
Sexes Eligible for Study: | ALL |
Accepts Healthy Volunteers: | 1 |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
Universtity of Michigan Health System
Ann Arbor, Michigan, United States, 48109