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NCT06646991 | NOT YET RECRUITING | Oxygen Toxicity


Comparison of Several Oxygenation Targets With Different Oxygen Interfaces - Impact on Oxygen Flow Rates
Sponsor:

Laval University

Information provided by (Responsible Party):

François Lellouche

Brief Summary:

Oxygen therapy is at the heart of the healthcare system. Oxygen flow rates depend on a number of confounding factors confounding factors (target used, skin pigmentation, pulse oximeter used, etc.) The investigators have recently have recently demonstrated that the combination of these factors (different peripheral oxygen saturation (SpO2) targets and different oximeters) can have a significant impact on oxygen flows rates. The effect on oxygen flow was not simply additive . The aim of this study is to evaluate the impact of the interface used on oxygen flow rates in different patient populations (main objective). The investigatoers also evaluate the impact of the interface on carbon dioxide (PaCO2), in particular with closed oxygen masks, with which rebreathing is theoretically possible (secondary objective). secondary objective).

Condition or disease

Oxygen Toxicity

COPD Bronchitis

Respiratory Failure

Intervention/treatment

Nasal canula - up to 6 liters per minute

Nasal canula - up to 15 liters per minute

Open oxygen mask

Simple oxygen face mask

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 20 participants
Masking : NONE
Primary Purpose : SUPPORTIVE_CARE
Official Title : Comparison of Several Oxygenation Targets With Different Oxygen Interfaces - Impact on Oxygen Flow Rates
Actual Study Start Date : 2024-12
Estimated Primary Completion Date : 2025-06
Estimated Study Completion Date : 2025-12

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Adult (\> or = 18 years old)
  • * Ongoing on conventional oxygen therapy with peripheral oxygen saturation (SpO2) between 88 and 100% with the usual oximeter
  • * SpO2 \< 92% ambient air with the usual oximeter
Exclusion Criteria
  • * No SpO2 signal with with the usual oximeter
  • * False nails or nail polish
  • * Severe anemia documented on last blood count during current hospitalization (haemoglobin (Hb) \< 80g/L)
  • * Oxygen flow \> 6 L/min

Comparison of Several Oxygenation Targets With Different Oxygen Interfaces - Impact on Oxygen Flow Rates

Location Details

NCT06646991


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Locations


Not yet recruiting

Canada,

University Institute of Cardiology and Pneumology of Quebec

Quebec, Canada, G1V4G5

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