University of Pittsburgh
Adriane Soehner
The goal of this neuroimaging pilot study is to understand developmental differences in the impact of therapeutic wavelength light (blue light) versus a non-therapeutic wavelength (red light) on emotional brain function in depression. The main questions this study aims to answer are: Does acute exposure to blue light (vs red light) stabilize emotional brain function in depressed individuals? Are stabilizing effects of blue light (vs red light) stronger for blue light in adolescents than young adults? Participants will complete: A magnetic resonance imaging brain scan, in which we will examine the effect of blue versus red light on emotional brain function at rest and in response to rewards and losses. A pupillometry test of sensitivity to blue vs red light Clinical interviews and surveys Screening measures for drug and alcohol use, MRI safety, and current pregnancy [if relevant] Home sleep tracking with sleep diary and actigraphy for one week
Depression in Adolescence
Depression in Adults
Blue Light
Red Light
Not Applicable
Study Type : | Interventional |
Estimated Enrollment : | 80 participants |
Masking : | None (Open Label) |
Primary Purpose : | Other |
Official Title : | Neuro-affective Response to Light in Depressed Adolescents and Young Adults |
Actual Study Start Date : | June 14, 2023 |
Estimated Primary Completion Date : | July 31, 2024 |
Estimated Study Completion Date : | July 31, 2024 |
Arm | Intervention/treatment |
---|---|
Experimental: Blue then Red Light Blue light (480 nm) then Red light (640 nm) |
Other: Blue Light Other: Red Light |
Experimental: Red Light then Blue Light Red light (640 nm) then Blue light (480 nm) |
Other: Blue Light Other: Red Light |
Ages Eligible for Study: | 12 Years to 30 Years |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Recruiting
Western Psychiatric Hospital
Pittsburgh, Pennsylvania, United States, 15213