Assistance Publique Hôpitaux de Paris
The purpose of this study is to describe the progression of tissular and functional myocardial abnormalities in patients with Duchenne muscular dystrophy using cardiac magnetic resonance imaging and blood biomarkers assays.
Duchenne Muscular Dystrophy
Cardiac MRI
Blood assays
Not Applicable
This study is to describe the progression of tissular (late gadolinium enhancement, T1, T2, ECV assessments) and functional (segmental and global contractility, strain) myocardial abnormalities in patients with Duchenne muscular dystrophy using cardiac magnetic resonance imaging and blood biomarkers assays (troponin I, NTproBNP). Comparison between baseline and 2-years assessments will be conducted.}}
| Study Type : | Interventional |
| Estimated Enrollment : | 150 participants |
| Masking : | None (Open Label) |
| Primary Purpose : | Diagnostic |
| Official Title : | Prospective Cardiac Magnetic Resonance Imaging Study in Duchenne Muscular Dystrophy (DMD-CMP) |
| Actual Study Start Date : | November 2024 |
| Estimated Primary Completion Date : | February 2029 |
| Estimated Study Completion Date : | April 2029 |
| Arm | Intervention/treatment |
|---|---|
|
Experimental: DMD-CMP cohort Minor (≥ 6 years) and major patients with genetically proven Duchenne myopathy |
Diagnostic Test: Cardiac MRI Biological: Blood assays |
| Ages Eligible for Study: | 6 Years |
| Sexes Eligible for Study: | Male |
| Accepts Healthy Volunteers: | No |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Not yet recruiting
Necker Hospital
Paris, France, 75015