Colorado State University
The purpose of this study is to determine optimal task design parameters for the measurement of transcranial magnetic stimulation (TMS) effects on cognition.
Cognitive Function
Transcranial Magnetic Stimulation
Not Applicable
Transcranial magnetic stimulation (TMS) is a non-invasive form of brain stimulation that relies on rapidly changing magnetic fields to influence neuronal firing rates. TMS can be used to temporarily inhibit or enhance the firing of populations of neurons located in the cerebral cortex. TMS-induced cortical inhibition versus enhancement is increasingly being used as a tool for exploring brain-behavior relationships and for improving cognitive functioning in people experiencing cognitive deficits due to neuropsychiatric illness (e.g., dementia and schizophrenia). However, important and unresolved methodological issues in this field concern the optimal design of cognitive tasks for TMS stimulation protocols. The purpose of this study is to determine optimal design protocols for online TMS studies of cognitive processes involved in attention, learning, and memory. Research participants will complete cognitive tasks while active versus sham (i.e., non-stimulating) TMS is applied to the brain. A factorial design will be used to determine the combination of task and TMS parameters (i.e., device settings) that produce the most robust and reliable behavioral effects.}}
Study Type : | Interventional |
Estimated Enrollment : | 100 participants |
Masking : | Single |
Masking Description : | Participants are blinded to TMS therapy, sham control |
Primary Purpose : | Other |
Official Title : | Brain Stimulation Effects on Cognitive Task Performance |
Actual Study Start Date : | April 20, 2023 |
Estimated Primary Completion Date : | January 1, 2025 |
Estimated Study Completion Date : | January 1, 2025 |
Arm | Intervention/treatment |
---|---|
Experimental: Active TMS Repetitive TMS for the brain |
Device: Transcranial Magnetic Stimulation |
Placebo Comparator: Sham TMS Scalp stimulation that does not affect the brain. |
Device: Transcranial Magnetic Stimulation |
Ages Eligible for Study: | 18 Years to 65 Years |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Accepts Healthy Volunteers |
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Recruiting
Colorado State University Department of Psychology
Fort Collins, Colorado, United States, 80523