Nikki Nollen, PhD, MA
Nikki Nollen, PhD, MA
This study will compare the efficacy of menthol-flavored versus tobacco-flavored 4th generation nicotine salt-based pod-system e-cigarettes in facilitating a switch from combustible cigarettes to e-cigarettes in adult menthol smokers.
Smoking Reduction
Menthol-flavored electronic cigarette
Tobacco-flavored electronic cigarette
Not Applicable
Menthol smokers (n=800), stratified by race, will be randomized 1:1 into a 12-week open label, non-inferiority trial comparing a 4th generation nicotine salt-based pod-system e-cigarette in menthol- versus tobacco-flavored e-liquid. Follow-up will continue through week 26. The primary outcome is rate of switching from combustible cigarettes to e-cigarettes at week 12.}}
| Study Type : | Interventional |
| Estimated Enrollment : | 800 participants |
| Masking : | None (Open Label) |
| Primary Purpose : | Prevention |
| Official Title : | The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers |
| Actual Study Start Date : | November 8, 2022 |
| Estimated Primary Completion Date : | June 30, 2025 |
| Estimated Study Completion Date : | November 30, 2025 |
| Arm | Intervention/treatment |
|---|---|
|
Active Comparator: Menthol Flavor Electronic Cigarette 400 adult cigarette smokers will receive 12 weeks of menthol-flavored electronic cigarettes. |
Other: Menthol-flavored electronic cigarette |
|
Active Comparator: Tobacco Flavor Electronic Cigarette 400 adult cigarette smokers will receive 12 weeks of tobacco-flavored electronic cigarettes. |
Other: Tobacco-flavored electronic cigarette |
| Ages Eligible for Study: | 21 Years |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | Accepts Healthy Volunteers |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Recruiting
University of Kansas Medical Center
Kansas City, missouri, United States, 64130