M.D. Anderson Cancer Center
To test a new investigational virtual exercise program for adolescents and young adults (AYAs) with brain tumors who plan to receive cranial radiotherapy
Brain Tumor
Brain Cancer
Standard Fitbit Program
Virtual Exercise Program
Not Applicable
Primary Objective: Determine the feasibility and acceptability of a virtually supervised exercise intervention compared to control in AYAs with brain tumors undergoing cranial radiotherapy (CRT). Secondary Objective: Assess the effect of supervised exercise intervention on the neuroanatomic structure and cognitive function changes in AYAs with brain tumors undergoing CRT. Exploratory Objective: Assess the effect of supervised exercise intervention on other brain structure (white matter integrity), cognitive functions (attention, visual learning, psychomotor function, executive function, verbal learning, working memory and clinician-reported neurological exam outcomes), patient-reported health-related quality of life, objectively measured and patient-reported physical activity level, patient-reported dietary recall, objectively measured physical function assessments, and exercise progression (exercise volume). Assess the agreement between physical function tests performed twice virtually.
Study Type : | Interventional |
Estimated Enrollment : | 40 participants |
Masking: | None (Open Label) |
Primary Purpose: | Supportive Care |
Official Title: | A Virtually Delivered Exercise Intervention To Mitigate Cognitive Deficits From Radiotherapy In AYAs With Brain Tumors |
Actual Study Start Date : | June 5, 2023 |
Estimated Primary Completion Date : | February 29, 2024 |
Estimated Study Completion Date : | February 29, 2024 |
Arm | Intervention/treatment |
---|---|
Experimental: Actigraph A device worn on the waist that measures physical activity (such as the number of steps participants walk each day, how long participants spend standing, and how long partticipants spend laying down). Participants should wear the ActiGraph at least 10 hours a day for 7 days. |
Behavioral: Standard Fitbit Program Behavioral: Virtual Exercise Program |
Ages Eligible for Study: | 15 Years to 39 Years |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Recruiting
M D Anderson Cancer Center
Houston, Texas, United States, 77030