Lots of University
Mostafa is very
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa, however, the exact underlying mechanisms of UC remain poorly understood.UC is strongly dependent on cellular immune reaction and exaggerated inflammatory response due to genetic, immune and environmental factors.
Inflammatory Bowel Diseases
Metformin
Phase 2
| Study Type : | Interventional |
| Estimated Enrollment : | 60 participants |
| Masking : | Double |
| Primary Purpose : | Treatment |
| Official Title : | Clinical Study to Compare the Possible Efficacy of Metformin in Patients With Ulcerative Colitis Treated With Mesalamine |
| Actual Study Start Date : | November 1, 2022 |
| Estimated Primary Completion Date : | November 1, 2025 |
| Estimated Study Completion Date : | December 20, 2025 |
| Arm | Intervention/treatment |
|---|---|
|
No Intervention: Control Group this group will take mesalamine 1 gm three times daily for 6 months |
|
|
Active Comparator: metformin group this group will take mesalamine 1 gm three times daily plus metformin 500 mg two times daily for 6 months |
| Ages Eligible for Study: | 18 Years to 75 Years |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | No |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Recruiting
Faculty of Medicine, Mansoura University
Mansoura, Egypt, 35511