Sohag University
Order of Ahmed Youssef Abdel Karim
Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder that is characterized by heterogeneous presentation at the clinical and molecular levels. ITGA4 protein has been found to be deregulated in CLL with adverse clinical outcome. ITGA4 gene (CD49d) encodes a member of the integrin alpha chain family of proteins and is considered a negative prognosticator in CLL with aggressive course and short time to treatment. The aim of the study: is to investigate ITGA4 gene expression pattern and to explore its methylation heterogeneity in CLL.
Chronic Lymphocytic Leukemia
| Study Type : | Observational |
| Estimated Enrollment : | 80 participants |
| Official Title : | ITGA4 Gene Methylation Status in Chronic Lymphocytic Leukemia |
| Actual Study Start Date : | July 1, 2022 |
| Estimated Primary Completion Date : | August 1, 2023 |
| Estimated Study Completion Date : | October 1, 2023 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | Accepts Healthy Volunteers |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.