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NCT05362565 | Not yet recruiting | Monogenic Obesity


Genetic Research of Monogenic Obesity in a Pediatric Cohort With Severe and Early Onset Obesity
Sponsor:

University Hospital, Bordeaux

Brief Summary:

Obesity is a frequent disease mainly caused by environmental/polygenic factors and more rarely caused by the alteration of a single gene ("monogenic obesity"). The diagnosis of these rare forms can lead to personalized management (new treatments, prognosis, adapted hygienic and dietary rules) and family screening. The use of a panel covering the known causes of monogenic obesity on a pediatric cohort of severe and early obesity will allow to evaluate the relevance of these analyses to adapt the management of this type of patients.

Condition or disease

Monogenic Obesity

Intervention/treatment

Salivary Sampling

Study Type : Observational
Estimated Enrollment : 100 participants
Official Title : Genetic Research of Monogenic Obesity in a Pediatric Cohort With Severe and Early Onset Obesity
Actual Study Start Date : October 1, 2022
Estimated Primary Completion Date : October 1, 2023
Estimated Study Completion Date : January 1, 2024

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 2 Years to 17 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Criteria
Inclusion Criteria
  • Recruitment age: 2-17 years
  • Body mass index, greater than the International Obesity Task Force (IOTF) 30 curve before the age of 5
  • Care at the specialized pediatric obesity center (CSO) of the Bordeaux University Hospital
  • Informed consent signed
Exclusion Criteria
  • no informed consent

Genetic Research of Monogenic Obesity in a Pediatric Cohort With Severe and Early Onset Obesity

Location Details


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Genetic Research of Monogenic Obesity in a Pediatric Cohort With Severe and Early Onset Obesity

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Locations


Not yet recruiting

France,

Bordeaux University Hospital Center

Bordeaux, France, 33400

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