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NCT05142020 | Active, not recruiting | Gestatiaonl Diabetes Mellitus


Biomarkers for Early Screening of Gestational Diabetes Mellitus
Sponsor:

Women's Hospital School Of Medicine Zhejiang University

Brief Summary:

Gestational Diabetes Mellitus (GDM) refers to the abnormal glucose metabolism first detected during pregnancy. It is estimated that approximately 7% of pregnant women worldwide and their offspring are affected by GDM. The incidence of GDM in China is as high as 18.9%. A number of studies have shown that GDM complicates 3%-25% of pregnancies and poses serious health and life threats to the mother and child. In fact, due to the lack of physical activity during pregnancy and the decrease of insulin sensitivity compared with non-pregnancy, the optimal time for intervention has long been lost until the diagnosis of GDM in the second trimester. However, it is a pity that no authoritative screening method for GDM in early pregnancy has been established, and the pathogenesis of GDM is still unclear. This study intend to search for biomarkers used for screening of GDM in early pregnancy and explore the pathogenesis of GDM, so as to provide new ideas for prevention measures and treatment targets of GDM.

Condition or disease

Gestational Diabetes Mellitus

Early Pregnancy

Study Type : Observational
Estimated Enrollment : 480 participants
Official Title : Study on Early Screening Biomarkers of Gestational Diabetes Mellitus and Its Related Pathogenesis
Actual Study Start Date : January 1, 2022
Estimated Primary Completion Date : August 22, 2022
Estimated Study Completion Date : December 31, 2023

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 20 Years to 49 Years
Sexes Eligible for Study: Female
Accepts Healthy Volunteers: Accepts Healthy Volunteers
Criteria
Inclusion Criteria
  • Maternal age: 20-49 years
  • Plan to have routine prenatal examinations and give birth in the research center
  • Willing to cooperate with the hospital to follow up
Exclusion Criteria
  • Have diseases that affect metabolic function or even threaten the life of the mother and fetus before pregnancy, such as diabetes, hypertension, heart disease, liver and kidney diseases, thyroid diseases, autoimmune diseases, malignant tumors, AIDS, etc.
  • Fetus has a known deformity or genetic defects
  • Incomplete clinical data

Biomarkers for Early Screening of Gestational Diabetes Mellitus

Location Details


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Biomarkers for Early Screening of Gestational Diabetes Mellitus

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


Not yet recruiting

China, Zhejiang

Dan please Chen

HangZhou, Zhejiang, China, 310006

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