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NCT05139329 | Unknown status | Myocarditis

The ORCHESTRATE-Myocarditis Registry
Sponsor:

Kansas City Heart Rhythm Research Foundation

Brief Summary:

A retrospective, observational study consisting of patients who presents with typical/atypical chest pain and have an ensuing negative ischemic evaluation

Condition or disease

Myocarditis

Ischemia

Chest Pain

Intervention/treatment

Imaging

Detailed Description:

Multicenter, retrospective, observational study consisting of patients who presents with typical/atypical chest pain to the emergency department and have an ensuing negative ischemic evaluation. Planned to review the subsequent diagnostic process in these patients, including patients with CMRI (Cardiac Magnetic Resonance Imaging), PET (Positron Emission Tomography) imaging for evaluation of myocarditis with the goal of quantifying the number of patients who go on to have a proven diagnosis of myocarditis that can explain their presenting symptoms.}}

Study Type : Observational
Estimated Enrollment : 382 participants
Official Title : Observational Registry of Ischemia Negative Chest Pain as the Presentation of Underlying Myocarditis: the ORCHESTRATE-Myocarditis Registry
Actual Study Start Date : January 2022
Estimated Primary Completion Date : March 2022
Estimated Study Completion Date : May 2022

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Criteria
Inclusion criteria
  • Age >18 years
  • Patients with a presentation of typical or atypical chest pain (ICD-10 Code R07.89, R07. 9)
  • Patients with a negative ischemic workup: (including Coronary Artery Calcium Scoring/CTA, MPI, Nuclear Stress test, LHC/angiography showing anything greater than "non-obstructive CAD")
  • Exclusion criteria
  • Patients with any evidence of positive ischemic workup as the cause of typical/atypical chest pain (as seen on Coronary Artery Calcium Scoring/CTA, MPI, Nuclear Stress test, LHC/angiography)
  • Previously documented history of Prinzmetal angina or coronary vasospasm
  • History of prior myocardial infarction
  • History of any prior CAD with severity greater than "non-obstructive CAD" in all 3 coronary arteries
  • History of LVEF<40%
  • Previously documented history of pericarditis
  • Previously documented history of costochondritis
    • The ORCHESTRATE-Myocarditis Registry

    Location Details

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    The ORCHESTRATE-Myocarditis Registry

    How to Participate

    Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

    Locations

    Not yet recruiting

    United States, California

    Loma Linda University International Heart Institute

    Loma Linda, California, United States, 92354

    Not yet recruiting

    United States, Kansas

    Kansas City Heart Rhythm Institute

    Overland Park, Kansas, United States, 66211

    Not yet recruiting

    United States, New York

    Montefiore Medical Center

    Bronx, New York, United States, 10467

    Not yet recruiting

    United States, Texas

    Texas Cardiac Arrhythmia Institute at St. David's Medical Center

    Austin, Texas, United States, 78705