McMaster University
Stuart Phillips
The present investigation aims to study a novel plant based protein isolate blend to determine if it results in similar muscle building responses compared to whey protein isolate.
Nutrition, Healthy
Protein quality
Not Applicable
Whey protein is considered the 'gold standard' to maintain body proteins (muscle, skin, bone). When isolated from milk, whey protein isolate (WPI) contains all nine essential amino acids (EAA) which are 'building blocks' that are needed to support the maintenance of body proteins. To date, there is no plant-based protein (PBP) isolate that compares to the recommended WPI towards how our body builds or supports our muscles. WPI is considered the 'gold standard' because it contains all of the EAA which provide the right amount of 'building blocks' to support our muscles. Current PBP isolates available contain insufficient amounts of EAA, and are less digestible, resulting in less 'building blocks' available to support our muscles. Recently, plant protein combinations have been designed to provide the right amounts of all the EAAs. Therefore, the aim of the present study is to determine the effects of a novel PBP blend on muscle protein synthesis responses by comparing it to WPI.
Study Type : | Interventional |
Estimated Enrollment : | 8 participants |
Masking: | Double |
Masking Description: | The study design will be a randomized, double blind, crossover trial. |
Primary Purpose: | Treatment |
Official Title: | Aminoacidemia and Protein Kinetics in Response to the Ingestion of Plant-based Protein Blends |
Actual Study Start Date : | August 15, 2022 |
Estimated Primary Completion Date : | April 1, 2023 |
Estimated Study Completion Date : | July 10, 2024 |
Arm | Intervention/treatment |
---|---|
Experimental: Whey protein isolate Whey protein isolate is the 'gold standard' of protein supplements due to being rich in essential amino acids and leucine. Leucine is a key amino acid the is required to stimulate muscle protein synthesis. Muscle protein synthesis is the major mechanism the underpins muscle growth. The whey protein would ostensibly serve as a positive control. |
Dietary Supplement: Protein quality |
Experimental: Plant based protein isolate Current plant-based protein isolates available contain insufficient amounts of leucine, and are less digestible, resulting in a reduced muscle protein synthesis responses. The plant based protein would ostensibly serve as a negative control. |
Dietary Supplement: Protein quality |
Experimental: Plant based protein isolate + leucine Enriching plant-based protein with leucine will increase the 'quality' of said protein source and theoretically should have similar muscle protein synthetic responses to whey protein. |
Dietary Supplement: Protein quality |
Ages Eligible for Study: | 18 Years to 30 Years |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Accepts Healthy Volunteers |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Not yet recruiting
Changhyun Lim
Hamilton, Ontario, Canada, L8S 4K1