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NCT05137483 | Not yet recruiting | COPD


Cognitive Impairment and Upper Extremity Performance in COPD
Sponsor:

Izmir Katip Celebi University

Information provided by (Responsible Party):

Ilknur Naz

Brief Summary:

Within the scope of this study, COPD patients will be divided into two groups according to cognitive dysfunction. Pulmonary function test, COPD assessment scale, Mini-Mental State Examination and Montreal Cognitive Assessment Scale, 6 min pegboard ring test, grip strength measurement, Fatigue Impact Scale and St.George Respiratory Questionnaire will be applied to the groups.

Condition or disease

COPD

Upper Extremity

Upper Limb Function

Cognitive Impairment

Intervention/treatment

Functional tests

Detailed Description:

Although the mechanism of cognitive dysfunction in COPD is not clear, the reasons focused on are; decreased oxygen use, high carbon dioxide levels, increased inflammation and oxidative stress, decreased physical activity, peripheral vascular diseases, atherosclerosis, high or low blood pressure, cerebral vasoconstriction, increased intracranial pressure, accompanying comorbidities, smoking and genetic predisposition, brain damage and exacerbations have been reported. Few studies have shown that cognitive dysfunction is associated with functional performance. There are no studies on the effect of cognitive function on upper extremity performance and mechanisms of action in COPD patients. The aim of this study is to compare upper extremity functional capacities, respiratory functions, fatigue and quality of life in COPD patients with and without cognitive function impairment. Within the scope of this study, COPD patients will be divided into two groups according to cognitive dysfunction. Pulmonary function test, COPD assessment scale, Mini-Mental State Examination and Montreal Cognitive Assessment Scale, 6 min pegboard ring test, grip strength measurement, Fatigue Impact Scale and St.George Respiratory Questionnaire will be applied to the groups.

Study Type : Observational
Estimated Enrollment : 80 participants
Official Title: Comparison of Upper Extremity Functional Capacity, Respiratory Functions, Fatigue and Quality of Life in Chronic Obstructive Pulmonary Patients With and Without Cognitive Impairment
Actual Study Start Date : November 19, 2021
Estimated Primary Completion Date : June 30, 2022
Estimated Study Completion Date : July 30, 2022

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 45 Years
Sexes Eligible for Study: All
Criteria
Inclusion Criteria
  • Volunteering to participate in the study
  • Stage 2-3-4 according to the GOLD classification in the 40-65 age range
Exclusion Criteria
  • Exacerbation of respiratory symptoms in the past 4 weeks (change in breathlessness and/or sputum volume/color, need for antibiotic treatment or need for hospitalization)
  • Presence of asthma, unstable coronary heart disease, uncontrolled diabetes, hypertension, left-sided congestive heart failure, neoplasia, severe claudication, encephalitis or epilepsy
  • Having a history of head trauma or brain tumor
  • Having a significant psychiatric condition or the presence of defined dementia, according to the American Psychiatric Association

Cognitive Impairment and Upper Extremity Performance in COPD

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Cognitive Impairment and Upper Extremity Performance in COPD

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