Insel Group AG, University Hospital Bern
Comparison of high-resolution optical coherence tomography (High-Res-OCT) to conventional imaging modalities for the diagnosis of eye diseases
Retinal Disease
Retinal Detachment
Retinal Vein Occlusion
Retinal Dystrophy
Retinal Artery Occlusion
Retinal Edema
Retinal Neovascularization
Uveitis
Diabetic Retinopathy
Diabetic Macular Edema
Macular Edema
Macular Degeneration
Macular Disease
Glaucoma
Optic Nerve Diseases
Hypertensive Retinopathy
High-resolution optical coherence tomography (High-Res-OCT)
Standard spectral domain OCT (SD-OCT)
The high resolution optical coherence tomography (High-Res-OCT) is an improvement of a non-invasive routinely used imaging technique, the optical coherence tomography (OCT), with a light-source capable of providing an increased axial resolution. The routinely used Spectral-Domain OCT has a center wavelength of 880 nm and a spectral bandwidth of 40 nm, resulting in an axial resolution of approximately 7 μm in the eye and is used routinely worldwide. The High-Res OCT works with a central wavelength of 840 nm and an increased bandwidth of 130 nm, making it possible to improve the optical axial resolution in tissue from 7 to 3 µm, without increasing the maximum laser exposure limit. The improved axial resolution of the High-Res OCT results in clearer and more detailed images. The technique is routinely used in clinical practice and the device used for High-Res-OCT (Heidelberg, SPECTRALIS® High-Res OCT- DMR001) has received CE mark (european conformity in the extended Single Market in the European Economic Area) approval in March 2021. We plan to compare High-Res-OCT as an imaging modality to conventional imaging modalities used in clinical routine, such as the Spectral-Domain-OCT (SD-OCT)}}
Study Type : | Observational |
Estimated Enrollment : | 550 participants |
Official Title : | Investigation of Retinal Pathology in Eye Diseases Using High Resolution Optical Coherence Tomography (High-Res-OCT) |
Actual Study Start Date : | November 30, 2021 |
Estimated Primary Completion Date : | November 30, 2023 |
Estimated Study Completion Date : | November 30, 2023 |
Information not available for Arms and Intervention/treatment
Ages Eligible for Study: | 18 Years |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Accepts Healthy Volunteers |
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Recruiting
Department of Ophthalmology, Bern University Hospital, Bern, 3010 Bern, Switzerland
Bern 3010, Bern, Switzerland, 3010